Page 44 - Mansoura National University

Biochemistry I Course – Level 2
“MNU Journey to Discover, Simplify, Merge the Interests of Visual Design

and Science”

This advanced educational project was implemented to deepen students’ understanding of
biochemical macromolecules—particularly polypeptides—through interactive, visual, and
application-based learning. Recognizing the importance of visual literacy in modern scientific
education, the activity integrated tools like PyMOL for 3D molecular visualization, hands-on
molecular modeling "ball-and-stick models", and BioRender for professional scientific
illustration. The project was divided among three student groups, each addressing complementary
aspects of peptide structure and function.

• Group 1 utilized PyMOL to visualize three-dimensional protein structures, recognize secondary
and tertiary structural features (such as α-helices and β-sheets), identify hydrogen bonding
patterns, and understand protein-ligand interactions.
• Group 2 focused on constructing physical ball-and-stick models to demonstrate molecular
bonding, using tactile materials to represent atoms and bonds, reinforcing spatial awareness of
atomic structure.
• Group 3 provided in-depth pharmacological insight by analyzing the selected polypeptide’s
mechanism of action, clinical formulations, FDA-approved uses, and side effects. They
presented this information as high-quality, visually compelling illustrations using BioRender.

The activity cultivated a wide array of academic and
professional skills. Students improved their grasp of core
biochemistry concepts by linking theory to visual and
physical representations. They developed problem-
solving skills as they learned to navigate software tools,
manage structural data, and create clear, scientific
visualizations. Collaborative learning fostered teamwork,
time management, adaptability, and effective
communication. Importantly, the project also bridged
scientific analysis with visual storytelling, enhancing
students’ ability to translate complex molecular
knowledge into accessible, accurate, and aesthetically
meaningful content. This multifaceted initiative not only
strengthened students’ technical and analytical abilities,
but also prepared them to engage with evolving
biotechnological tools and scientific communication
methods, crucial skills for future professionals in
pharmacy, biomedical research, and health sciences.

42 Faculty of Pharmacy Newsletter